Institute of NeuroPhysiopathology

The Institute of NeuroPhysiopathology (INP), UMR7051 (CNRS-AMU) develops high-level fundamental, applied and translational research in neuroscience, leading to applications in the biomedical field, whether in industry or the clinic. The INP’s research strategy focuses on two main areas: neurodegenerative diseases and neuro-oncology, which are fueled by the study of cross-disciplinary mechanisms involved in neuronal ang glial cell plasticity, neuroinflammation and neurovascular interactions, cytoskeletal organization, the brain’s immune microenvironment, post-injury repair and learning and memory. These themes are underpinned by strong expertise developed by INP teams over the years in the fields of Alzheimer’s disease, glioblastoma, multiple sclerosis and cytoskeletal regulation at the molecular and cellular level.

The INP also includes 4 technology platforms (PFNT): The “Neuro-Cellular Imaging Support” (NCIS) imaging platform, accredited as a Nikon Center of Excellence, the “Timone Molecular Interactions Platform” (PINT), the “Stem Cell Center NeuroTimone” (SCeNT) platform, and the Preclinical and Translational Neuro-oncology Research platform (PETRA’Tech)
Together with the biotechnology company Vect-Horus (40 persons), the INP (120 persons) constitutes a Labcom (public-private partnership) dedicated to developing strategies against brain disease involving the crossing of the blood-brain barrier.

Pictures from the INP laboratory