Neurone d'hippocampe étiqueté pour l'actine (orange), la synapsine (vert) et map2 (bleu).
AMU/CNRS Christophe Leterrier

Institute of NeuroPhysiopathology

The Institute of NeuroPhysiopathology (INP), UMR7051 (CNRS-AMU) develops high-level fundamental, applied and translational research in neuroscience, leading to applications in the biomedical field, whether in industry or the clinic. The INP’s research strategy focuses on two main areas: neurodegenerative diseases and neuro-oncology, which are fueled by the study of cross-disciplinary mechanisms involved in neuronal ang glial cell plasticity, neuroinflammation and neurovascular interactions, cytoskeletal organization, the brain’s immune microenvironment, post-injury repair and learning and memory. These themes are underpinned by strong expertise developed by INP teams over the years in the fields of Alzheimer’s disease, glioblastoma, multiple sclerosis and cytoskeletal regulation at the molecular and cellular level.

The INP also includes 4 technology platforms (PFNT): The “Neuro-Cellular Imaging Support” (NCIS) imaging platform, accredited as a Nikon Center of Excellence, the “Timone Molecular Interactions Platform” (PINT), the “Stem Cell Center NeuroTimone” (SCeNT) platform, and the Preclinical and Translational Neuro-oncology Research platform (PETRA’Tech)
Together with the biotechnology company Vect-Horus (40 persons), the INP (120 persons) constitutes a Labcom (public-private partnership) dedicated to developing strategies against brain disease involving the crossing of the blood-brain barrier.

Pictures from the INP laboratory

INP platforms

Discover the NeuroTimone stem cell platform at the INP (don't forget to enable the English subtitles)

Neural Plasticity and Degeneration

Description

To find out more, click on the following link : here

Team leader

Santiago Rivera

Synaptic Degeneration and Gliosis

Description

To find out more, click on the following link : here

 

Team leader

Maud Gratuze

Blood Brain Barrier and Neuroinflammation

Description

To find out more, click on the following link : here

Team leader

Michel Khrestchatisky

Oligodendroglial Cell Lineage in Aging and in Disease

Description

To find out more, click on the following link : here

Team leader

Sarah Moyon

SInBioSE (Système nerveux, Inflammation et BIOmarqueurs de la Sclérose En plaques)

Description

To find out more, click on the following link : here

Team leader

Sophie Desplat-Jégo

Stem cells, Disease modeling and Neuroregeneration

Description

To find out more, click on the following link : here

Team leader

Emmanuel Nivet

NeuroCyto: the neuronal cytoskeleton in health and disease

Description

To find out more, click on the following link : here

Team leader

Christophe Leterrier

GlioME: Gliomagenesis and MicroEnvironment

Description

To find out more, click on the following link : here

Team leader

Aurélie Tchoghandjian

Emeline Tabouret

Molecular Interactions and Pharmacology

Description

To find out more, click on the following link : here

Team leader

Hervé Kovacic

François Devred

Angiogenesis and Tumor Microenvironment

Description

To find out more, click on the following link : here

Team leaders

L'Houcine Ouafik

NOSE. Nasal Olfactory Stemness and Epigenesis

Description

To find out more, click on the following link : here

Team leaders

Gaëlle Guiraudie-Capraz

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