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- Biomarker research
- Clinical Studies
- Molecular exploration
Bio Markers at INT / Neuro-Bio-Tools (BioMINT / NBT)
Protein and genomic biomarkers
BioMINT offers research into protein or genomic biomarkers in neurosciences for diagnosis and clinical or pre-clinical physiopathological monitoring) . It has a secure environment (L2) for receiving and processing human samples and equipments allow highly reproducible immunoassays and quantification and nucleic acids RNA extraction.
Ella is a Benchtop Automated ELISA Platform. In less than 90 minutes, it provides highly reproducible validated assay data and consistent biomarker detection with no manual steps.
Jess automates the protein separation and immunodetection of traditional Western blotting, eliminating many of the tedious, error-prone steps. It allows high sensitivity multiplexing (chemiluminescent and fluorescent detection channels and RePlexing capabilities) and provides results in 3 to 5 hours
NBT also has an environment dedicated to molecular biology, enabling the purification of nucleic acids(genomic DNA, total RNA from human blood samples) and the quantification of biomarkers using real time RT qPCR.
Technics
- ELISA (Enzyme Linked ImmunoSorbent Assay)
- Nucleic Acid Purification
- Westernblot (protein immunodetection)
Equipments
- ELLA (Automated Immuno Analysis, Simple Plex ELISA)
- Jess (automated simple western blot)
Numbers!
With Ella, single Plex assays quantify up to 16, 32, or 72 samples in triplicate, multianalyte assays allow to quantify 2, 3, or 4 target analytes in parallel in triplicate, multiplex assays allow to quantify 5, 6, 7, or 8 analytes in duplicate.. Simplex and multiplex assays are available for human samples and also mouse and rat targets using only 2.5 to 25µl.
Jess gets down to picogram-level sensitivity with just 3 µL of starting material and offers 13 or 25 sample capillary cartridges
Training
You are looking for a platform to train one or more staff on a particular technique or equipment?
In this platform training in the use of Jess and Ella equipments and nucleic acids purification is possible.
