Mosaic team

Affiliate Team MOSAIC (Fresnel Institute)

mosaic team

Presentation of the Institute

Created in 2000, the Fresnel Institute builds on high scientific expertise in various topics related to the physics of waves. More recently, other activities at the crossroads of biology, biophysics and biomedical imaging emerged. The research topics of the lab currently cover four axes: electromagnetic modelling and simulation, nanophotonics and optical components, information processing and random waves, and advanced imaging and life sciences. The synergies between these axes are very strong and give rise to novel projects, often at the frontier between different disciplines. These projects can be fundamental or applied, with a strong potential for innovation, which the lab supports through several technological platforms. The Fresnel Institute is supported by several institutions, Aix-Marseille Université, CNRS and Centrale Marseille. Nearly two hundred persons work today in the lab, with a total budget of about 9 M€.



Mosaic is an interdisciplinary research group aiming at unravelling life science problems using advanced photonic tools.

Mosaic principal investigators are physicists and biologists working together at the cross roads between advanced optical imaging, nanophotonics and tissue morphogenesis.

In parallel, the Mosaic group is involved in collaborative projects related to the fields of developmental biology, immunology, neurosciences and biomedical research.

Team leader

Hervé Rigneault: 8 HDRs


  • Sparse/random illumination microscopy,
  • fluorescence correlation spectroscopy,
  • single-molecule imaging,
  • scanning electron microscopy,
  • polarisation microscopy,
  • wavefront shaping,
  • confocal microscopy,
  • quantitative phase imaging,
  • temperature microscopy,
  • non-linear microscopy,
  • Raman spectroscopy,
  • thin-fibre endoscopy,
  • photoacoustic imaging

Research axes

Optics, Nanosciences, Biology


Morphogenesis, nanobiophotonics, polarisation, deep-tissue imaging, thermoplasmonics, phase imaging, label-free microscopy, neurophotonics 

  • Animal Cognition And Behavior
  • Autonomic And Neuroendocrine Systems
  • Computational Neuroscience
  • Development Of The Nervous System 
  • Disorders Of The Nervous System
  • Excitability
  • Excitability, Synaptic Transmission, Network Functions
  • Human Cognition And Behavior
  • Motor Systems
  • Network Functions
  • Novel Methods And Technology Development
  • Sensory Systems
  • Sleep
  • Sleep, Autonomic And Neuroendocrine Systems
  • Synaptic Transmission
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