NeuroSchool seminar: Sonia Garel

Seminar by Sonia Garel

Neurobiologist and head of the Brain Development and Plasticity team at the Institut de biologie de l’École normale supérieure in Paris.

On Monday, 30 September, 2024, the NeuroSchool PhD Program is inviting Sonia Garel, at INMED, Luminy Campus, to give a seminar on the The many roles of microglia in brain wiring: a developmental perspective.

This seminar will present Microglia, the main resident immune cells of the brain, can undergo major cellular and transcriptomic changes, a remarkable feature observed during development, ageing and disease. Over the past decades, microglia were shown to key and diverse roles in brain wiring and their dysfunction has been linked to the etiology of almost all brain disorders, from neurodevelopment to neurodegeneration. Thus, grasping how and when microglia shape circuits is important for both neurobiologists and clinicians.

Our goal is to explore the contribution of microglia to early brain development, when these cells constitute a main glial population. Here, we will summarize published and unpublished work highlighting emerging roles of microglia in the construction of the developing brain, including a novel role in the maintenance of tissue integrity during embryonic morphogenesis. We will discuss the implications for neurodevelopmental disorders and, more broadly, the interest of using normal development to decrypt the kaleidoscope of microglial activities and states.

The schedule is as follows:

• 10 am – Discussion among students to discuss the papers  – For PhD students only
• 11 am – Seminar – Open to all – INMED conference room
• 12 pm – Special discussion time with the speaker for PhD students onlyheet in order for your hours to be counted. Attendants get 3 hours, chairpersons 4 hours.