Description de la soumission d'un avis
Internship
Search for new functions of oligodendrocyte progenitor cells: from behavior to electrophysiology
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The objective of this project is to get insight into unknown functions of oligodendrocyte precursor cells (OPC) in the adult brain. We will characterize a new mouse line generated in the lab in which OPC can be thoroughly killed in a very specific and time-controlled manner. These mice will be submitted to a battery of behavioral tests and then sacrificed for histological and electrophysiological analyses (patch clamp on hippocampal slices).
This study will hopefully help understanding if and how OPC modulate brain function.