Based on our previous results, our working hypothesis is that endogenous oxytocin plays a determining role, at key developmental stages, in shaping feeding, social behavior and learning abilities. In our team, we aim to define those impactful developmental time windows during which a lack of OT secretion is critical and will alter those behaviors with a long term effect. Using viruses and pharmacogenetics tools, we aim to silent transiently OT neurons in wild-type mice at different postnatal developmental stages and during a chosen period. Following this inactivation, we will measure different behavioral, cellular and molecular parameters which have been previously identified to be modulated by oxytocin.
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